CBY1/PGEA1 antibody

Catalog No. ABIN7112690

The Rabbit Polyclonal anti-CBY1/PGEA1 antibody has been validated for IHC, ELISA, WB and IP. It is suitable to detect CBY1/PGEA1 in samples from Human, Mouse and Rat.

Quick Overview for CBY1/PGEA1 antibody (ABIN7112690)

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CBY1/PGEA1 Antibody

Purpose: CBY1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: chibby homolog 1(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: CBY1

Background:

Synonyms: Protein chibby homolog 1|ARPP-binding protein|Cytosolic leucine-rich protein|PIGEA-14|PKD2 interactor, Golgi and endoplasmic reticulum-associated 1|CBY1|ARB1|C22orf2|CBY|PGEA1

Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

Molecular Weight: 30-35 kDa

Gene ID: 25776

UniProt: Q9Y3M2